Indications:

Vitamin D is important for calcium homeostasis, bone me­ tabolism and neuromascular function.Fero-D is indicated in vitamin D deficiency or insufficiency due to lacK of exposure to sunlight.or insufficient diet. During pregnancy for healthy fetus development. Other symptomatic conditions include Rickets,osteoporosis, osteomalacia and osteopenia.

Mode of Action:

Cholcalciferolis inactive form of vitamin 03. After adminis­ tration,the first step involved in the activation is a 25- hydroxylation which is catalysed by the 25-hydroxy lase in the liver and then in the kidney by other enzymes. The active form of vitamin 03is calcitriol. Calcitriolappears to promote intestinalabsorption of calcium through binding to the vita­ min D receptor in the mucosal cytoplasm of the intestine. Subsequently,calcium is absorbed through formation of a calcium-binding protein.

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